diagnostic case reports

In research applications we offer a detailed report on ICP pressure variations via surrogate ICP waveform morphology that can better support diagnostics


Application and context

Hydrocephalus is a disease caused by the abnormal accumulation of cerebrospinal fluid in the brain in one or more ventricular sinuses, causing changes in brain compliance and clinical manifestations such as headaches (intensified when the person is lying down and improved when sitting or standing), mental confusion, and losses of memory and balance. It can affect adults and children and differential diagnosis is often difficult and time-consuming, as imaging tests may be non-specific.

In adults, hydrocephalus may occur due to other diseases, such as strokes, brain tumors, trauma, and intracranial hemorrhages. In children, growth entails the need for periodic surgeries to replace ventriculoperitoneal shunts.

How brain4care may contribute to the diagnosis of hydrocephalus

Case 1 – hydrocephalus in an adult

Case 2 – pediatric hydrocephalus

verification of vps valve proper function

Application and context

People with hydrocephalus have an abnormal accumulation of cerebrospinal fluid in one or more ventricular sinuses, causing a change in brain compliance. The treatment of these patients includes the surgical implantation of a valve that drains excess fluid and maintains the central nervous system in equilibrium (VPS valve). Even with the valve implanted, these patients may present clinical manifestations such as headaches, mental confusion, as well as loss of memory and balance. Determining whether or not the cause of the manifestations is related to the inadequate functioning of the valves can be difficult, especially when the results of the imaging tests do not correspond to the patients’ clinical picture.

how brain4care helps in verifying the operation of vps valves

clinical case 1 – intracranial hypertension caused by infections of the central nervous system (cns)

intracranial hypertension caused by central nervous system (cns) infections

Application and context

Intracranial hypertension (ICH) is a clinical condition characterized by increased pressure inside the skull, compressing all structures of the brain, causing, among other things, permanent loss of vision and even death.

One of the possible causes of ICH is a CNS infection. They are very serious, caused by neglect in treating infectious diseases of other parts of the body, loss of immune response and infections related to health care (iatrogenesis).

The diagnosis of CNS infection is simple, but the identification of ICH requires invasive procedures (lumbar puncture).

how brain4care contributes to diagnose CNS infections

clinical case 1 – intracranial hypertension caused by infections of the central nervous system (cns)